There are a few different amp settings that you'll need to adjust on your guitar amplifier in order to get the best sound.
The first is the gain setting, which controls the amount of distortion in your sound. If you're looking for a clean sound, you'll want to keep the gain low. If you're looking for a heavier sound, you'll want to turn the gain up.
The next setting is the EQ, or equalization. This controls the treble, midrange, and bass levels in your sound. You'll want to experiment with this until you find a balance that you like.
The last setting is the volume. This one is pretty self-explanatory - turn it up until it's as loud as you want it.
With these settings, you should be able to get a pretty good sound out of your guitar amplifier. Experiment with them until you find a sound that you like.